Funding for the project reportedly comes from investors ranging from Climate Capital to the Winklevoss Twins
A new biotechnology company is aiming to genetically regenerate the woolly mammoth by 2027.
Colossal, which launched on Monday, has received $15 million in initial funding for the project.
on its websiteIn this article, the company discussed the issue of extinction and the goal of “developing an animal extinction library as well as housing genetic DNA/embryos from endangered animals.”
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“This process will slow the long-term effects of human-induced loss of biodiversity and give threatened species a buffer against outright extinction as numbers dwindle,” the site read.
“Our lab’s results will directly address issues related to loss in biodiversity and overall species count resulting from human-accelerated degradation of land, sea and air. Ultimately, the aim is to achieve this by reintroducing important animal and plant species.” has played an active role in the conservation of some of Earth’s most climate-remunerative ecosystems, many of which have disappeared completely today,” Colossal said.
the company quoted 10 “basic truths” as reasons to revive the furry, toothy animal, including an effort to mitigate the effects of climate change, restore the Arctic, save modern elephants from extinction, and promote advances in multiplex CRISPR genome editing “.
CRISPR, colossal explained, is an “engineered cellular technique used to identify and cut a specific code of DNA inside the nucleus.”
“Once this DNA is cut, a laboratory modified version of the DNA is inserted and the cut DNA is reassembled by binding to a specific code,” the company said.
Development of cold resistant hybrid elephant wild again In the Siberian tundra – equipped with all the main biological traits of a woolly mammoth – is already in process, according to Colossal.
“Our teams have collected viable DNA samples, and are editing the genes that will allow this amazing megafauna to once again rumble through the Arctic,” the company wrote.
Using CRISPR genome editing, CRISPR works with an enzyme called Cas9 to modify genes.
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“A CRISPR-Cas9 complex would use a single guide RNA from CRISPR to cleave and recognize a specific sequence of DNA, where the Cas9 molecule would cleave strands that are complementary to the CRISPR sequence. This laboratory engineered the re-insertion of DNA. … eventually, giving us the ability to insert cold-resistant characteristics into elephant DNA – leading to the extinction of the woolly mammoth,” Colossal continued.
“So bringing back the woolly mammoth is not just a theory. It is a science that has been developed and mastered by George Church, PhD, and his lab,” it said. “With 99.6% genetic matching in the Asian elephant, intact giant DNA and modern genetic engineering, work is well underway.”
Colossal was founded by Harvard Medical School biologist Church and tech entrepreneur Ben Lam.
“Never before has humanity been able to harness the power of this technology to rebuild ecosystems, heal our Earth, and preserve our future through the re-population of extinct animals.” Lam said in a statement:. “In addition to bringing back ancient extinct species such as the walleye mammoth, we will be able to leverage our technologies to preserve critically endangered species on the brink of extinction and to help restore animals where humankind lives. had a hand in his death.”
Colossal will support research in Church’s lab and others in Boston and Dallas, According to The New York Times.
Funding for the project, the paper said, comes from investors ranging from Climate Capital to the Winklevoss twins.
However, many people in the area have voiced their doubts about hybridized Asian elephants.
“It’s not just about their survival, but making sure that once they do exist and live a prosperous life,” says S. Matthew Liao, a New York University bioethicist on the scientific advisory board of Colossal. told National Geographic. “Otherwise, you are being cruel to these animals.”